The Holland Land Office Museum presents the history of Genesee County, New York. Topics covered include the Tonawanda Indian Reservation, the Seneca people, military history, and Victorian life. The collection contains approximately 16,000 artifacts—2,000 of which are available for viewing at a given time. The collection is supplemented by a series of temporary exhibits.

The museum offers exhibits, customizable tours, and more than 15 summer education programs. Reservations are required for tours.